Sabrina, yes, I think enemies to friends can be satisfying because the author has to have a conflict that keeps the two MCs apart until the end. What we want to see is the MCs overcoming that conflict. In stories without that trope, the author has to work harder to find a realistic conflict to keep the MCs apart.
Back when I was an AE, I once acquired an historical romance where the hero had Asperger’s tendencies and I adored the way the author compassionately wove the issues this created for him into the overall storyline; he didn’t have to change to be worthy of love. It was wonderful!